Mellemgaard A, Carstensen B, Nørgaard N, Knudsen J B, Olsen J H
Danish Cancer Society, Danish Cancer Registry, Institute for Cancer Epidemiology, Copenhagen.
Scand J Urol Nephrol. 1993;27(3):327-32. doi: 10.3109/00365599309180442.
Temporal trends in the incidence of cancer of the renal parenchyma, renal pelvis, ureter, bladder, urethra and Wilm's tumor in the period 1943-88 were described. Log-linear Poisson models were used to estimate the changes over time and the geographical variations. We have found a steep increase in the incidence of pelvis and ureter cancer; and to some extent also for bladder cancer in men. The incidence of cancer of the renal parenchyma has increased more moderately while the rates of Wilm's tumor have been virtually stable throughout the period. These findings suggest that tumors in the urinary system differ with respect to risk factors and should be grouped by their histological origin as well as topographical site.
描述了1943年至1988年期间肾实质癌、肾盂癌、输尿管癌、膀胱癌、尿道癌和威尔姆斯瘤的发病率的时间趋势。使用对数线性泊松模型来估计随时间的变化和地理差异。我们发现肾盂和输尿管癌的发病率急剧上升;男性膀胱癌在一定程度上也是如此。肾实质癌的发病率上升较为平缓,而威尔姆斯瘤的发病率在整个时期基本稳定。这些发现表明,泌尿系统肿瘤在危险因素方面存在差异,应根据其组织学起源和解剖部位进行分组。