Obaturov G M, Filimonov A S
Radiats Biol Radioecol. 1993 Sep-Oct;33(5):717-23.
The latest experimental findings in the field of radiation-induced structural mutagenesis especially concerned with the role of the DNA double strand breaks (DSBs) in the formation of chromosome aberrations were analyzed. It was shown slow-repairable and non-repairable DSBs appeared to be the DNA critical damages leading to aberrations.
分析了辐射诱导结构诱变领域的最新实验结果,尤其关注DNA双链断裂(DSB)在染色体畸变形成中的作用。结果表明,缓慢修复和不可修复的DSB似乎是导致畸变的DNA关键损伤。