The combination of coculture and selective assisted hatching: results from their clinical application.
作者信息
Wiemer K E, Hu Y, Cuervo M, Genetis P, Leibowitz D
机构信息
Northwest Center for Infertility and Reproductive Endocrinology, Margate, Florida.
出版信息
Fertil Steril. 1994 Jan;61(1):105-10. doi: 10.1016/s0015-0282(16)56461-9.
OBJECTIVE
To establish pregnancies using a combination of coculture and selective assisted hatching.
DESIGN
Clinical application for a selected group of patients. Not a controlled study.
SETTING
Private infertility practice.
PATIENTS
Women with high basal FSH levels, ovulatory disorders, and multiple failed IVF attempts.
MAIN OUTCOME MEASURES
Pregnancy and implantation rates.
RESULTS
Of the 95 patients who had coculture and selective assisted hatching, 45 (47.0%) have an ongoing pregnancy with a 23.0% implantation rate.
CONCLUSION
The combination of coculture and assisted hatching produced acceptable pregnancy and implantation rates within the selected patient population.
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