青霉属菌株产生的新型抗球虫剂海那培烯A、B和C。II. 结构解析。

Hynapenes A, B and C, new anticoccidial agents produced by Penicillium sp. II. Structure elucidation.

作者信息

Tabata N, Tomoda H, Iwai Y, Omura S

机构信息

Research Center for Biological Function, Kitasato Institute, Tokyo, Japan.

出版信息

J Antibiot (Tokyo). 1993 Dec;46(12):1854-8. doi: 10.7164/antibiotics.46.1854.

DOI:10.7164/antibiotics.46.1854

PMID:8294244

Abstract

The structures of hynapenes A, B and C, novel anticoccidial agents, were determined by spectroscopic analyses. Hynapenes A, B and C were deduced to be (2E,4E)-5-(1,3,4-trihydroxy-2,6,8-trimethyldecalin)-2,4-p entadienoic acid, (2E,4E)-5-(1-ene-3-oxo-2,6,8-trimethyldecalin)-2,4-pentad ienoic acid and (2E,4E)-5-(3-ene-1-oxo-2,6,8-trimethyldecalin)-2,2,4-pent adienoic acid, respectively.

摘要

新型抗球虫剂海那戊烯A、B和C的结构通过光谱分析确定。海那戊烯A、B和C分别推断为(2E,4E)-5-(1,3,4-三羟基-2,6,8-三甲基十氢化萘)-2,4-戊二烯酸、(2E,4E)-5-(1-烯-3-氧代-2,6,8-三甲基十氢化萘)-2,4-戊二烯酸和(2E,4E)-5-(3-烯-1-氧代-2,6,8-三甲基十氢化萘)-2,2,4-戊二烯酸。