Cytosaminomycins, new anticoccidial agents produced by Streptomyces sp. KO-8119. II. Structure elucidation of cytosaminomycins A, B, C and D.
作者信息
Shiomi K, Haneda K, Tomoda H, Iwai Y, Omura S
机构信息
Research Center for Biological Function, Kitasato Institute, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1994 Jul;47(7):782-6. doi: 10.7164/antibiotics.47.782.
PMID:8071123
Abstract
Structures of novel anticoccidial antibiotics, cytosaminomycins A, B, C and D, were elucidated by NMR studies. Cytosaminomycins were shown to be nucleoside antibiotics related to oxyplicacetin. Their carboxylic acid moieties bonded to the cytosine residue were different from that of oxyplicacetin. The carboxylic acids contained in cytosaminomycins A, B, C and D were (E)-3-(methylthio)acrylic acid, 4-methylaminobenzoic acid, 3-methylcrotonic acid, and tiglic acid, respectively.
摘要
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