单克隆丙种球蛋白病患者的凝血障碍
Coagulation disorders in patients with monoclonal gammopathies.
作者信息
Keren D F
机构信息
Warde Medical Laboratory, Ann Arbor, Michigan.
出版信息
Hematol Oncol Clin North Am. 1993 Dec;7(6):1153-9.
PMID:8294313
Abstract
Monoclonal gammopathies can present as disorders of coagulation whether the gammopathy is due to a malignant B-cell lymphoproliferative disorder or a monoclonal gammopathy of undetermined significance. Detection of the monoclonal gammopathy involves quantification of immunoglobulins including kappa and lambda along with high-resolution electrophoresis of serum. Immunofixation is occasionally needed on serum and always needed on urine for the final diagnosis.
摘要
单克隆丙种球蛋白病可表现为凝血障碍，无论该丙种球蛋白病是由恶性B细胞淋巴增殖性疾病引起，还是意义未明的单克隆丙种球蛋白病。单克隆丙种球蛋白病的检测包括免疫球蛋白（包括κ和λ）定量以及血清的高分辨率电泳。最终诊断时，血清偶尔需要进行免疫固定电泳，而尿液则始终需要进行免疫固定电泳。
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