Grossman D, Rapini R P, Osborne B, Duvic M
Department of Dermatology, Baylor College of Medicine, Houston, TX 77030.
J Am Acad Dermatol. 1994 Feb;30(2 Pt 2):313-5. doi: 10.1016/s0190-9622(94)70030-3.
A patient with mycosis fungoides that had progressed to tumor stage responded to chemotherapy and electron beam treatment, but 6 years later a peripheral neuropathy, extensive plaques, erythroderma, and enlarged pinnae containing acid-fast organisms developed while he was being treated with photopheresis. The skin lesions cleared with administration of rifampin and dapsone, but a reversal reaction biopsy specimen showed features of both mycosis fungoides and leprosy. This case raises the question of whether there may be an association between mycosis fungoides and leprosy.
