Fam A G, Rubenstein J
Divison of Rheumatology, Sunnybrook Health Science Centre, University of Toronto, ON, Canada.
J Rheumatol. 1993 Oct;20(10):1731-40.
The steady decline in tuberculosis rates in Canada has led to a certain lack of awareness of the disease. We describe 7 patients with culture proven spinal tuberculosis, seen in a teaching hospital over a 10-year period. Persistent spinal pain and local tenderness were the most frequent presenting findings. There was a mean delay in diagnosis of 5.2 (range 1-18) months from the time of presentation. Only 2 patients had active extraspinal tuberculous infection. Plain spinal radiographs were the initial diagnostic procedure of choice showing a destructive vertebral lesion in 5 of 7 patients. Computed tomography (CT) played an important role in delineating the discovertebral lesion and in demonstrating a paraspinal soft tissue infection in 6 (85%) of 7 patients: psoas abscess in 4 (2 with epidural extension), epidural abscess in one, and a neck abscess in one. Magnetic resonance imaging (MRI) in one patient enabled a more complete definition of the vertebral infection and its soft tissue extensions. Two patients were successfully treated with combination antituberculous chemotherapy alone, and 5 required adjuvant surgical procedures. Our study stresses the need for increased alertness to this now uncommon but treatable spinal infection, and emphasizes the diagnostic usefulness of CT and MRI in defining subtle discovertebral lesions and in detecting unsuspected paravertebral soft tissue extension.
加拿大结核病发病率的持续下降导致了人们对该疾病的某种程度的忽视。我们描述了在一家教学医院10年间收治的7例经培养证实的脊柱结核患者。持续性脊柱疼痛和局部压痛是最常见的临床表现。从出现症状到确诊的平均延迟时间为5.2个月(范围1 - 18个月)。只有2例患者有脊柱外活动性结核感染。脊柱X线平片是最初选择的诊断方法,7例患者中有5例显示有椎体破坏性病变。计算机断层扫描(CT)在明确椎体病变以及显示7例患者中6例(85%)的椎旁软组织感染方面发挥了重要作用:4例为腰大肌脓肿(2例伴有硬膜外扩展),1例为硬膜外脓肿,1例为颈部脓肿。1例患者的磁共振成像(MRI)能够更完整地明确椎体感染及其软组织扩展情况。2例患者仅通过联合抗结核化疗成功治愈,5例需要辅助手术治疗。我们的研究强调需要提高对这种现在虽不常见但可治疗的脊柱感染的警惕性,并强调CT和MRI在明确细微椎体病变以及检测未被怀疑的椎旁软组织扩展方面的诊断价值。