Gansburgskiĭ A N, Pavlov A V
Ontogenez. 1993 Nov-Dec;24(6):79-82.
Regeneration of endothelium after the local cryodestruction of the aortic wall in rats was studied using quantitative methods (determination of the pool of proliferating cells after multiple injections of 3H-thymidine, of the mitotic index and proportion of binucleated cells, and cytophotometry of DNA content in cell nuclei). It is demonstrated that binucleate endotheliocytes are formed as the result of acytokinetic mitosis. According to our calculations, this mechanism completely provides for the increase in the proportion of binucleated cells observed in the regenerating endothelium on days from 2 to 6 after the operation.
采用定量方法（多次注射³H-胸腺嘧啶核苷后测定增殖细胞池、有丝分裂指数和双核细胞比例，以及细胞核DNA含量的细胞光度测定法）研究了大鼠主动脉壁局部冷冻破坏后内皮的再生情况。结果表明，双核内皮细胞是无胞质分裂有丝分裂的结果。根据我们的计算，该机制完全解释了术后第2至6天再生内皮中观察到的双核细胞比例增加的现象。
