Polosukhin V V, Egunova S M, Chuvakin S G
Probl Tuberk. 1993(5):37-41.
Seventy specimens of bronchoalveolar lavage were obtained from 30 patients with pulmonary tuberculosis during treatment with endobronchial laser. The lavage is shown to undergo marked qualitative and quantitative changes in response to He-Ne laser treatment: the proportion of macrophages goes up while that of neutrophils tends to a decrease. The laser is capable to induce metabolic and proliferative activity of alveolar macrophages indicated by RNA and DNA synthesis. Morphological alterations in the cells of the respiratory compartment suggest weakening of exudative-necrotic component of the inflammation as an underlying cause of laser efficacy.
从30例接受支气管内激光治疗的肺结核患者中获取了70份支气管肺泡灌洗样本。结果显示，灌洗样本在接受氦氖激光治疗后发生了显著的定性和定量变化：巨噬细胞比例上升，而中性粒细胞比例趋于下降。激光能够诱导肺泡巨噬细胞的代谢和增殖活性，这通过RNA和DNA合成得以体现。呼吸腔室细胞的形态学改变表明，炎症渗出-坏死成分的减弱是激光发挥疗效的潜在原因。
