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[支气管内激光治疗期间肺结核支气管活检的超微结构及放射自显影研究]

[Ultrastructural and radioautographic study of bronchial biopsy in pulmonary tuberculosis during endobronchial laser therapy].

作者信息

Polosukhin V V, Egunova S M, Chuvakin S G

出版信息

Probl Tuberk. 1994(4):44-8.

PMID:7984616
Abstract

Structural and metabolic changes were explored in 68 main bronchial mucosal biopsy specimens from 31 patients with fibrocavernous pulmonary tuberculosis. It was shown that He-Ne laser endobronchial therapy induced proliferative and metabolic processes (as judged from the level of DNA and RNA syntheses) in the damaged epithelium, which restored its structure and differentiation into celiary and goblet cells with normal ultrastructure having undergone a number of transitional forms. The proliferative and metabolic activity of endotheliocytes and stromal cells increased in the intrinsic layer of the mucosa, which was accomplished by formation of soft fiber connective tissue.

摘要

对31例纤维空洞型肺结核患者的68份主支气管黏膜活检标本进行了结构和代谢变化的研究。结果表明,氦氖激光支气管内治疗可诱导受损上皮细胞发生增殖和代谢过程(从DNA和RNA合成水平判断),使其结构得以恢复,并分化为具有正常超微结构的纤毛细胞和杯状细胞,且经历了多种过渡形式。黏膜固有层内内皮细胞和基质细胞的增殖和代谢活性增强,这通过形成软纤维结缔组织得以实现。

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