Amofah G K, Sagoe-Moses C, Adjei-Acquah C, Frimpong E H
Ministry of Health, Kumasi, Ghana.
Trans R Soc Trop Med Hyg. 1993 Nov-Dec;87(6):644-5. doi: 10.1016/0035-9203(93)90272-r.
This paper describes 90 cases of Buruli ulcer in Amansie West district, Ghana. 49% were below 15 years of age while 20% were over 50 years. There was a significant difference in the age and sex composition, with more males among the younger age groups than females but the converse among adults. Seasonal variation is described, with peak incidence in September and October. Cases who had received bacillus Calmette-Guérin (BCG) vaccination had a shorter duration of the ulcer than those who were not vaccinated. No such association was found between BCG vaccination and the age of onset of the disease. There was no significant difference between cases and controls regarding their BCG vaccination status. There is an urgent need to regard Buruli ulcer in Ghana more seriously.
本文描述了加纳阿曼西西区的90例布鲁里溃疡病例。49%的患者年龄在15岁以下，而20%的患者年龄超过50岁。年龄和性别构成存在显著差异，较年轻年龄组中男性多于女性，而成年人中则相反。文中描述了季节性变化，9月和10月发病率最高。接种过卡介苗（BCG）的病例溃疡持续时间比未接种者短。未发现卡介苗接种与疾病发病年龄之间存在此类关联。病例组和对照组在卡介苗接种状况方面没有显著差异。加纳迫切需要更严肃地对待布鲁里溃疡。
