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犊牛代谢性酸中毒的诊断与治疗:一项实地研究。

Diagnosis and treatment of metabolic acidosis in calves: a field study.

作者信息

Grove-White D H, White D G

机构信息

Department of Farm Animal Medicine, Royal Veterinary College, University of London, Hatfield, Hertfordshire.

出版信息

Vet Rec. 1993 Nov 13;133(20):499-501. doi: 10.1136/vr.133.20.499.

DOI:10.1136/vr.133.20.499
PMID:8296434
Abstract

The history and results of a clinical examination were recorded for 32 spring-born suckler calves which were hospitalised for intravenous fluid therapy. Blood samples were taken before treatment, during treatment and before discharge and analysed for colostral status, total carbon dioxide as an indication of acid-base status, and haematocrit. All the calves were given intravenously 5 to 10 litres of electrolyte solution containing 144 mmol/litre sodium, 4 mmol/litre potassium, 113 mmol/litre chloride and 35 mmol/litre bicarbonate, supplemented, in 24 calves, with up to 450 ml of 1M sodium bicarbonate. Nearly all the calves were recumbent but less than half were dehydrated on admission. The signs of dehydration were well correlated with each other and with the haematocrit. Neither the history nor the clinical signs were useful predictors of acidosis. There was no relationship between the severity of acidosis and the degree of dehydration. Acidosis was more prevalent in older calves (P < 0.01). For the severely acidotic calves, supplementary intravenous fluid with sodium bicarbonate significantly (P < 0.05) improved the total blood carbon dioxide at discharge. All 32 calves recovered. It is possible to treat acidotic calves with intravenous fluid therapy effectively, economically and according to their individual needs. The Harleco apparatus is a simple, useful, cost-effective adjunct to the diagnosis and treatment of this life-threatening condition.

摘要

记录了32头春季出生的哺乳犊牛的临床检查病史及结果,这些犊牛因静脉补液治疗而住院。在治疗前、治疗期间和出院前采集血样,分析初乳状态、作为酸碱状态指标的总二氧化碳以及血细胞比容。所有犊牛均静脉输注5至10升电解质溶液,该溶液含144毫摩尔/升钠、4毫摩尔/升钾、113毫摩尔/升氯和35毫摩尔/升碳酸氢盐,24头犊牛还补充了多达450毫升的1M碳酸氢钠。几乎所有犊牛入院时均呈卧姿,但不到一半存在脱水。脱水体征之间以及与血细胞比容之间相关性良好。病史和临床体征均不是酸中毒的有效预测指标。酸中毒严重程度与脱水程度之间无关联。酸中毒在年龄较大的犊牛中更常见(P<0.01)。对于严重酸中毒的犊牛,补充含碳酸氢钠的静脉补液显著(P<0.05)改善了出院时的全血二氧化碳水平。所有32头犊牛均康复。采用静脉补液疗法可以根据酸中毒犊牛的个体需求,有效、经济地对其进行治疗。哈勒科仪器是诊断和治疗这种危及生命疾病的一种简单、实用且经济高效的辅助工具。

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