在血管炎长期管理中，通过酶联免疫吸附测定法检测疾病活动度与抗中性粒细胞胞浆抗体水平之间的关系。
Relationship between disease activity and ANCA level by ELISA in the long-term management of vasculitis.
作者信息
De'Oliviera J, Gaskin G, Dash A, Rees A J, Pusey C D
机构信息
Department of Medicine, Royal Postgraduate Medical School, London, UK.
出版信息
Adv Exp Med Biol. 1993;336:303-4. doi: 10.1007/978-1-4757-9182-2_47.
PMID:8296622
Abstract
Solid-phase immunoassays were used to examine the relationship between ANCA concentration and disease activity during follow-up of 63 patients with systemic vasculitis. ANCA levels fell with induction therapy. Relapses during long-term follow-up were generally associated with high or rising ANCA concentrations, although the temporal relationship between clinical relapse and changes in ANCA was variable.
摘要
采用固相免疫测定法，对63例系统性血管炎患者进行随访，以研究抗中性粒细胞胞浆抗体（ANCA）浓度与疾病活动度之间的关系。诱导治疗期间ANCA水平下降。在长期随访中，复发通常与ANCA浓度升高或上升有关，尽管临床复发与ANCA变化之间的时间关系是可变的。
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