系统性红斑狼疮（SLE）中对乳铁蛋白具有特异性的抗中性粒细胞胞浆抗体（ANCA）。
ANCA with specificity for lactoferrin in systemic lupus erythematosus (SLE).
作者信息
Sinico R A, Pozzi C, Radice A, Tincani A
机构信息
Divisione di Nefrologia, Ospedale S. Carlo, Milano, Italy.
出版信息
Adv Exp Med Biol. 1993;336:385-7. doi: 10.1007/978-1-4757-9182-2_66.
PMID:8296641
Abstract
Antibodies to lactoferrin were detected in about 20% of patients with SLE, irrespective of the presence of renal involvement and in 10% of patients with rheumatoid arthritis and in 19% of patients with scleroderma. We conclude that anti-lactoferrin antibodies may be found in different types of connective tissue disease. Their clinical significance in these diseases however remains to be elucidated.
摘要
在约20%的系统性红斑狼疮患者中检测到乳铁蛋白抗体，无论是否存在肾脏受累情况；在10%的类风湿关节炎患者以及19%的硬皮病患者中也检测到了该抗体。我们得出结论，抗乳铁蛋白抗体可能存在于不同类型的结缔组织病中。然而，它们在这些疾病中的临床意义仍有待阐明。
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