显微镜下多血管炎和韦格纳肉芽肿中抗内皮细胞抗体的证据不足。
Little evidence for anti-endothelial-cell antibodies in microscopic polyarteritis and Wegener's granulomatosis.
作者信息
Varagunam M, Nwosu A C, Adu D, Garner C, Taylor C M, Michael J, Thompson R A
机构信息
Renal Research Laboratory, Queen Elizabeth Hospital, Edgbaston, Birmingham.
出版信息
Adv Exp Med Biol. 1993;336:419-22. doi: 10.1007/978-1-4757-9182-2_73.
Sera from patients with a vasculitis and controls were investigated for the presence of anti-endothelial cell antibodies(AECA), anti- neutrophil cytoplasmic antibodies(ANCA) and anti-myeloperoxidase (MPO) antibodies. Only 19% of patients with Wegener's granulomatosis and 2% of patients with microscopic polyarteritis had AECA. Our data suggests that AECA are a minor antibody system in vasculitis.
对血管炎患者和对照组的血清进行检测，以确定是否存在抗内皮细胞抗体（AECA）、抗中性粒细胞胞浆抗体（ANCA）和抗髓过氧化物酶（MPO）抗体。韦格纳肉芽肿患者中只有19%、显微镜下多动脉炎患者中只有2%存在AECA。我们的数据表明，AECA在血管炎中是次要的抗体系统。
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