Shaker Z A, El-Raziky E H, Abou-El-Ezz F M, Mahmoud A H, Mousa A H
Egypt J Bilharz. 1976;3(2):221-32.
Circulating bilharzial antigens were demonstrated in 39% out of 87 bilharzial patients via the IHA and CF techniques using hyperimmune rabbit anti - S.mansoni worm serum. Correlation between the percentage of positive cases and the age, duration of infection, clinical presentation, type of bilharzial infection, chemotherapeutic effect and the intradermal test (I.D.T.) were made. The percentage of positive cases was found to increase with age and with the duration of infection. More positivity was encountered in hepatosplenomegalic and in S.mansoni-infected cases. Most of the I.D positive cases were also IHA positive, but still some I.D. negative cases were IHA positive. Specific chemotherapy resulted in rise in the number of IHA positive cases which was followed by gradual fall in teh next six months until they became negative. On the other hand, using the CF technique, all cases turned negative after treatment with no phase of augmentation. However, antigenaemia reappeared in few cases. These cases relapsed later. Comparing the results of IHA and CF indicates that each test may be detecting a different group of antigens.
通过使用超免疫兔抗曼氏血吸虫虫体血清的间接血凝试验（IHA）和补体结合试验（CF）技术，在87例血吸虫病患者中的39%检测到循环血吸虫抗原。分析了阳性病例百分比与年龄、感染持续时间、临床表现、血吸虫感染类型、化疗效果及皮内试验（IDT）之间的相关性。发现阳性病例百分比随年龄和感染持续时间增加。肝脾肿大患者和曼氏血吸虫感染病例中阳性率更高。大多数ID阳性病例IHA也呈阳性，但仍有一些ID阴性病例IHA呈阳性。特异性化疗导致IHA阳性病例数增加，随后在接下来的六个月中逐渐下降直至转阴。另一方面，使用CF技术，所有病例治疗后均转阴，无增加阶段。然而，少数病例中抗原血症再次出现。这些病例随后复发。比较IHA和CF的结果表明，每种检测方法可能检测到不同组别的抗原。
