Wiedow O, Lüdemann J, Utecht B, Christophers E
Department of Dermatology, University of Kiel, Germany.
Adv Exp Med Biol. 1993;336:61-4. doi: 10.1007/978-1-4757-9182-2_8.
Elafin and antileukoprotease are potent peptide-like inhibitors of human leukocyte elastase and have been isolated from human skin and bronchial mucus. Elafin proved to be a potent inhibitor of proteinase 3, whereas other inhibitors of human leukocyte elastase such as antileukoprotease and eglin C proved to be much less effective.
弹性蛋白酶抑制因子和抗白细胞蛋白酶是人类白细胞弹性蛋白酶的强效肽类抑制剂,已从人类皮肤和支气管黏液中分离出来。事实证明,弹性蛋白酶抑制因子是蛋白酶3的强效抑制剂,而其他人类白细胞弹性蛋白酶抑制剂,如抗白细胞蛋白酶和水蛭素C的效果则要差得多。