Fields J H, Grochowski S, Lindenmayer J P, Kay S R, Grosz D, Hyman R B, Alexander G
Department of Psychiatry, Albert Einstein College of Medicine/Montefiore Medical Center-Bronx Children's Psychiatric Center, NY 10461.
Am J Psychiatry. 1994 Feb;151(2):249-53. doi: 10.1176/ajp.151.2.249.
The purpose of this study was to test the reliability and validity of a new assessment instrument for positive and negative symptoms in severely disturbed children and adolescents (Kiddie-PANSS).
The Positive and Negative Syndrome Scale for adult schizophrenia was modified through successive field trials on the basis of developmental characteristics of children and adolescents. The scale was then given to 34 inpatients (19 children, mean age = 9.35 years, and 15 adolescents, mean age = 14.33 years) with DSM-III-R diagnoses of schizophrenia, psychosis not otherwise specified, schizoaffective, affective, conduct, personality, and developmental disorders determined independently by child psychiatrists. All patients with schizophrenia were placed in the schizophrenic group, and all others were placed in a general inpatient group. The Kiddie-PANSS ratings were given by three trained child psychiatrists after a 30-35-minute structured interview. The Achenbach Child Behavior Checklist, the Scale for the Assessment of Positive Symptoms, and the Scale for the Assessment of Negative Symptoms were also administered in order to determine criterion-related association.
Intraclass correlation coefficients revealed that all subscales and total psychopathology were reliably assessed among raters. The Kiddie-PANSS and Scale for the Assessment of Positive Symptoms/Scale for the Assessment of Negative Symptoms correlated with one another, indicating criterion-related association. Differences on measures of positive, negative, and general psychopathology, as measured by the Kiddie-PANSS, between the patients with schizophrenia and the general inpatient group were highly significant.
The Kiddie-PANSS shows good interrater reliability and criterion-related validity. In a cohort of inpatient children and adolescents the scale successfully differentiated schizophrenic patients from nonschizophrenic patients.
本研究旨在测试一种针对严重精神障碍儿童和青少年的正负症状新评估工具（儿童版阳性和阴性症状评定量表，Kiddie-PANSS）的信度和效度。
基于儿童和青少年的发育特征，通过连续的现场试验对成人精神分裂症的阳性和阴性症状量表进行修改。然后，将该量表施用于34名住院患者（19名儿童，平均年龄 = 9.35岁，15名青少年，平均年龄 = 14.33岁），这些患者由儿童精神科医生独立诊断为患有DSM-III-R精神分裂症、未另行规定的精神病、精神分裂情感障碍、情感障碍、品行障碍、人格障碍和发育障碍。所有精神分裂症患者被归入精神分裂症组，其他所有患者被归入普通住院组。三名经过培训的儿童精神科医生在进行30 - 35分钟的结构化访谈后给出Kiddie-PANSS评分。同时还施测了阿肯巴克儿童行为量表、阳性症状评估量表和阴性症状评估量表，以确定与标准相关的关联。
组内相关系数表明，所有分量表和总体精神病理学在评分者之间得到了可靠的评估。Kiddie-PANSS与阳性症状评估量表/阴性症状评估量表相互关联，表明与标准相关的关联。Kiddie-PANSS所测量的阳性、阴性和总体精神病理学指标在精神分裂症患者和普通住院组之间的差异非常显著。
Kiddie-PANSS显示出良好的评分者间信度和与标准相关的效度。在一组住院儿童和青少年中，该量表成功地区分了精神分裂症患者和非精神分裂症患者。
