Ugarte G, Cheng A, Gómez A, Segure T
G E N. 1976 Jul-Dec;31(1-2):65-73.
The effect of excessive alcohol intake on the protein requirements and metabolism in normal subjects has not been clearly determined. In this study we measured the nitrogen balance, the hematrocrit, the hemoglobin, the serum albumin, the cholesterol, and the plasmatic amino acids in 7 non-alcoholic subjects of 25 +/- 5 years of age. A comparison was made of a diet containing 0.8 g of protein per k of weight and 40 Kcal per k of weight administered during 11 days with a period of the same length in which the 1.400 Kcal provided during the control period by carbon hydrates was provided by ethanol (200 g). During the alcoholic period no importants changes were observed in the nitrogen balance, a tendency towards greater positivity being registered. There was a decrease in the serum albumin of 4, 69 +/- 0.31 vs 3, 90 +/- 0,32 g/100 ml and an increase in globulin 1,74 +/- 0,70 vs 2,69 +/- 0,22 g/100 ml. The results showed that in a short period of time the excessive alcohol intake in normal subjects does not increase the protein requirements in spite of a decrease in the serum albumin being observed.
过量饮酒对正常受试者蛋白质需求和代谢的影响尚未明确确定。在本研究中，我们测量了7名年龄在25±5岁的非酒精性受试者的氮平衡、血细胞比容、血红蛋白、血清白蛋白、胆固醇和血浆氨基酸。将体重每千克含0.8克蛋白质和每千克体重40千卡热量的饮食在11天内的情况，与相同时长的另一时期进行比较，在后一时期，对照期由碳水化合物提供的1400千卡热量由乙醇（200克）提供。在饮酒期间，氮平衡未观察到重要变化，但有向更大正值发展的趋势。血清白蛋白从4.69±0.31克/100毫升降至3.90±0.32克/100毫升，球蛋白从1.74±0.70克/100毫升增至2.69±0.22克/100毫升。结果表明，在短时间内，正常受试者过量饮酒尽管观察到血清白蛋白下降，但并未增加蛋白质需求。
