Ramesh S, Michaels J A, Galland R B
Department of Surgery, Royal Berkshire Hospital, Reading, UK.
Br J Surg. 1993 Dec;80(12):1531-3. doi: 10.1002/bjs.1800801212.
Since January 1988, 32 patients have presented with 44 popliteal aneurysms (22 thrombosed, 22 non-thrombosed). Patients with thrombosed aneurysms were older (median age 72 versus 66 years), and more likely to have bilateral lesions (P < 0.02) and serious associated cardiovascular disease (P < 0.02). Nineteen aneurysms thrombosed acutely; 12 were treated with intra-arterial thrombolysis, which was at least partially successful in seven. All 12 were subsequently bypassed, as were the other seven which were associated with such severe ischaemia that they required urgent operation. One patient died and two others required major amputation. Other complications included foot-drop (two patients), renal failure (one) and wound infection (two). Two grafts thrombosed and required re-exploration. Elective bypass was carried out in 11 patients without acutely thrombosed aneurysms; there were no significant postoperative problems. Distortion within the aneurysm (P < 0.01), large size (P < 0.01) and distortion of the popliteal artery above or below the lesion (P < 0.02) were all associated with thrombosis. Stenosis within the aneurysm was more likely in patients with multiple lesions (P < 0.01) and distortion with larger aneurysms (P < 0.01). After correcting for distortion, none of the other variables was independently significant. The combination of distortion and diameter > 3 cm was present in 13 of 15 thrombosed aneurysms. Morbidity is high following acute thrombosis of popliteal aneurysm. Distortion of the aneurysm appears to be a more sensitive predictor of thrombosis than size alone. The combination of distortion with a diameter > 3 cm may help to define popliteal aneurysms that should be bypassed electively.
自1988年1月以来,32例患者出现了44个腘动脉瘤(22个血栓形成,22个未血栓形成)。血栓形成的动脉瘤患者年龄较大(中位年龄72岁对66岁),更易出现双侧病变(P<0.02)和严重的相关心血管疾病(P<0.02)。19个动脉瘤急性血栓形成;12个接受了动脉内溶栓治疗,其中7个至少部分成功。所有12个随后都进行了旁路移植,另外7个因严重缺血需要紧急手术也进行了旁路移植。1例患者死亡,另外2例需要进行大截肢。其他并发症包括足下垂(2例)、肾衰竭(1例)和伤口感染(2例)。2个移植物血栓形成,需要再次探查。11例无急性血栓形成的动脉瘤患者进行了择期旁路移植;术后无重大问题。动脉瘤内的扭曲(P<0.01)、大尺寸(P<0.01)以及病变上方或下方腘动脉的扭曲(P<0.02)均与血栓形成有关。多个病变的患者动脉瘤内更易出现狭窄(P<0.01),较大动脉瘤的扭曲也更易出现狭窄(P<0.01)。校正扭曲因素后,其他变量均无独立显著性。15个血栓形成的动脉瘤中有13个存在扭曲和直径>3 cm的情况。腘动脉瘤急性血栓形成后发病率较高。动脉瘤的扭曲似乎是比单纯大小更敏感的血栓形成预测指标。扭曲与直径>3 cm的组合可能有助于确定应进行择期旁路移植的腘动脉瘤。