Check J H, Hourani C, Choe J K, Callan C, Adelson H G
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Department of Obstetrics and Gynecology, Cooper Hospital/University Medical Center, Camden.
Fertil Steril. 1994 Feb;61(2):262-4. doi: 10.1016/s0015-0282(16)56514-5.
Previous data suggested a subtle increase in serum P at the time of hCG injection without LH surge reduces the PR of women having oocyte retrievals for IVF; this study compared PRs of recipients in a shared oocyte program according to the donors' pre-hCG P level. There was no difference in viable PRs between recipients and donors when P < or = 1 ng/mL. The PR was similar for recipients when donors' P was > 1 ng/mL (12.7%). Donors with P > 1 ng/mL had the lowest PR: 7.2%. The data suggest that the adverse effect of higher serum P without LH surge may be on the endometrium rather than the oocyte.
先前的数据表明，在注射人绒毛膜促性腺激素（hCG）时血清孕酮（P）略有升高且无促黄体生成素（LH）峰，会降低接受体外受精（IVF）取卵女性的妊娠率（PR）；本研究根据供体hCG注射前的P水平，比较了共享卵母细胞计划中受体的PR。当P≤1 ng/mL时，受体和供体的活产PR没有差异。当供体的P>1 ng/mL时，受体的PR相似（12.7%）。P>1 ng/mL的供体PR最低：7.2%。数据表明，无LH峰时较高血清P的不良影响可能作用于子宫内膜而非卵母细胞。
