Lawton A W
Department of Ophthalmology, Louisiana State University School of Medicine, New Orleans.
Fertil Steril. 1994 Feb;61(2):390-1. doi: 10.1016/s0015-0282(16)56537-6.
A 31-year-old woman developed acute visual loss in her right eye immediately after a 5-day course of CC for primary infertility. Although she gradually recovered vision, she did not return to 20/20 acuity in that eye. As CC may cause vascular sludging, it is hypothesized that increased blood viscosity resulted in sufficiently reduced flow in a posterior ciliary artery to produce an anterior ischemic optic neuropathy. Patients experiencing visual symptoms while taking clomiphene should have their eyes examined promptly for evidence of visual changes or optic nerve injury.
一名31岁女性在接受克罗米芬（CC）治疗原发性不孕症5天后，右眼立即出现急性视力丧失。尽管她的视力逐渐恢复，但该眼并未恢复到20/20的视力。由于CC可能导致血管淤滞，因此推测血液粘度增加导致睫状后动脉血流充分减少，从而产生前部缺血性视神经病变。服用克罗米芬时出现视觉症状的患者应立即检查眼睛，以寻找视觉变化或视神经损伤的证据。
