Kaiser H J, Flammer J, Graf T, Stümpfig D
Universitäts-Augenklinik, Basel, Switzerland.
Graefes Arch Clin Exp Ophthalmol. 1993 Dec;231(12):677-80. doi: 10.1007/BF00919280.
Blood pressure was monitored for 24 h in 32 control patients, 38 open-angle glaucoma patients referred because of decompensated IOP despite maximum treatment, 40 patients with open-angle glaucoma referred because of progressive damage despite controlled IOP, and 39 normal-tension glaucoma patients. In the control group a physiological drop in blood pressure during the night was observed. The patients referred with uncontrolled IOP had blood pressure very similar to that of the control group during both day and night. However, the open-angle glaucoma patients with progression despite well-controlled IOP and also the patients with normal-tension glaucoma had markedly, and statistically significantly, lower systolic blood pressure during both day and night. The difference in diastolic blood pressure was smaller. Thus, blood pressure should be considered in diagnosis.
对32名对照患者、38名因尽管接受了最大程度治疗但眼压仍失代偿而转诊的开角型青光眼患者、40名因尽管眼压得到控制但仍有进行性损害而转诊的开角型青光眼患者以及39名正常眼压性青光眼患者进行了24小时血压监测。在对照组中观察到夜间血压生理性下降。眼压未得到控制而转诊的患者白天和夜间的血压与对照组非常相似。然而,眼压控制良好但仍有进展的开角型青光眼患者以及正常眼压性青光眼患者白天和夜间的收缩压均明显降低,且具有统计学意义。舒张压的差异较小。因此,在诊断中应考虑血压因素。