Senders C W, Tinling S P
Department of Otolaryngology-Head and Neck Surgery, University of California, Davis.
Int J Pediatr Otorhinolaryngol. 1993 Dec;28(1):33-9. doi: 10.1016/0165-5876(93)90144-r.
The explanation for the separation in the cricoid cartilage after the anterior cricoid split procedure has been a matter of speculation. Whether it is caused by extrinsic factors such as stenting, contraction of laryngeal muscles, fibrosis, or whether it is due to the intrinsic nature of the cricoid cartilage itself has yet to be defined. Whole organ in vitro cultures of juvenile gerbil cricoid cartilages were utilized to study the intrinsic response of cricoid cartilage to anterior vertical division. Our results showed the cricoid cartilage to immediately separate, and that separation to markedly increase during whole organ culture. These results suggest that while extrinsic factors may modify the gap after the anterior cricoid split procedure, the intrinsic nature of the cricoid cartilage itself results in the gap formation.
环状软骨前部劈开术后环状软骨分离的原因一直是个推测的问题。它是由诸如支架置入、喉肌收缩、纤维化等外在因素引起的，还是由于环状软骨本身的内在特性所致，尚未明确。利用幼年沙鼠环状软骨的全器官体外培养来研究环状软骨对前部垂直分割的内在反应。我们的结果显示环状软骨立即分离，且在全器官培养过程中分离明显增加。这些结果表明，虽然外在因素可能会改变环状软骨前部劈开术后的间隙，但环状软骨本身的内在特性导致了间隙的形成。
