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利用磁共振成像技术构建人体喉软骨的解剖模型。

Developing an anatomical model of the human laryngeal cartilages from magnetic resonance imaging.

作者信息

Selbie W Scott, Gewalt Sally L, Ludlow Christy L

机构信息

Laryngeal and Speech Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892-1416, USA.

出版信息

J Acoust Soc Am. 2002 Sep;112(3 Pt 1):1077-90. doi: 10.1121/1.1501586.

DOI:10.1121/1.1501586
PMID:12243156
Abstract

The purpose of this work was to construct a three-dimensional anatomical framework of the cartilages of the human larynx. The framework included representative surface models of the four laryngeal cartilages and estimated attachment points for the intrinsic laryngeal muscles. High-resolution magnetic resonance imaging (MRI) was used to scan one female and four male human cadaveric larynges. The cartilages were segmented manually from the MRI volume for analysis. Two of these larynges were subsequently dissected and the landmark distances on the cartilages measured for comparison with the MRI measures and previous studies. The MRI measures were 8% smaller than the anatomical measures and 12% smaller than data reported in the literature. A laryngeal coordinate system was defined using the plane of symmetry of the cricoid cartilage. Measures of cricoid cartilage symmetry had less than 3% difference between the two sides for a series of measures. An algorithm for registering larynges that minimized the root-mean-square distance between the surface of a reference cricoid cartilage and the surfaces of nonisotropically scaled candidate cricoid cartilages was evaluated. This study provided an anatomical framework for registering different larynges to the same coordinate space.

摘要

这项工作的目的是构建人类喉部软骨的三维解剖框架。该框架包括四个喉软骨的代表性表面模型以及喉内肌的估计附着点。使用高分辨率磁共振成像(MRI)扫描了一具女性和四具男性人类尸体的喉部。从MRI容积中手动分割出软骨进行分析。随后对其中两具喉部进行了解剖,并测量了软骨上的标志性距离,以便与MRI测量结果和先前的研究进行比较。MRI测量结果比解剖测量结果小8%,比文献报道的数据小12%。使用环状软骨的对称平面定义了一个喉部坐标系。对于一系列测量,环状软骨两侧的对称测量差异小于3%。评估了一种用于配准喉部的算法,该算法可使参考环状软骨表面与非各向同性缩放的候选环状软骨表面之间的均方根距离最小化。这项研究提供了一个用于将不同喉部配准到同一坐标空间的解剖框架。

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Developing an anatomical model of the human laryngeal cartilages from magnetic resonance imaging.利用磁共振成像技术构建人体喉软骨的解剖模型。
J Acoust Soc Am. 2002 Sep;112(3 Pt 1):1077-90. doi: 10.1121/1.1501586.
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