Sperm aspiration from vas deferens and in-vitro fertilization in cases of non-treatable anejaculation.

Spermatozoa were aspirated from the proximal vas deferens of five men with persistent anejaculation which could not be overcome by using a vibrator or electro-ejaculation. Three men had spinal cord injury, one man had undergone a pelvic lymphadenectomy, and in one of them the aetiology was unknown. Fairly good numbers of spermatozoa (from 7.5 to 170 million) with progressive motility from 24 to 75% were obtained from all the eight microsurgically performed aspiration attempts. In vitro fertilization (IVF) was successful in seven attempts. Eight embryo transfers (six with fresh and two with frozen embryos) resulted in three pregnancies. The pregnancy rates, 37% per aspiration and 37% per embryo transfer, show that in this small group of patients, aspiration of spermatozoa from the vas deferens followed by IVF-embryo transfer is a promising method in the management of infertility caused by persistent anejaculation.