Dahlberg A, Ruutu M, Hovatta O
Infertility Clinic, Family Federation of Finland, Helsinki, Finland.
Hum Reprod. 1995 Sep;10(9):2305-7. doi: 10.1093/oxfordjournals.humrep.a136290.
In an infertility treatment programme for spinal-cord injured men, vibrator application was primarily used in cases of upper motor neurone lesion and electroejaculation in men with lower lesions, or when vibrator application failed to induce ejaculation. Spermatozoa were obtained by these methods from 29 out of 35 men who desired infertility treatment. No ejaculate was obtained from six men. Three of these men plus two others with very poor sperm quality with electroejaculation underwent micro-surgical sperm aspiration from the vas deferens for invitro fertilization (IVF), and spermatozoa were obtained from all of them. Thus it was possible to obtain spermatozoa from almost every spinal-cord injured man who had ongoing spermatogenesis using these three methods. Insemination was the primary infertility treatment used with all the couples where there was successful ejaculation. In all, 12 pregnancies resulted from home vaginal inseminations, eight from intrauterine inseminations, two from IVF with ejaculated spermatozoa, and two from IVF with spermatozoa aspirated from the vas. Three couples had children from donor inseminations (not counted in the results); 12 are still in the programme. From 24 pregnancies, 22 children have now been born to 18 couples out of the original 35 (51%), and there were four abortions. Hence, overall, infertility treatment of spinal-cord injured men has given good results.
在一项针对脊髓损伤男性的不育治疗方案中，对于上运动神经元损伤的患者主要采用振动器刺激射精，对于下运动神经元损伤的患者或振动器刺激射精失败的患者则采用电刺激射精。35名希望接受不育治疗的男性中，有29名通过这些方法获取了精子。6名男性未获得精液。其中3名男性以及另外2名电刺激射精后精子质量极差的男性接受了输精管显微外科精子抽吸术以进行体外受精（IVF），他们均成功获取了精子。因此，使用这三种方法几乎可以从每一位仍在产生精子的脊髓损伤男性身上获取精子。对于所有射精成功的夫妇，授精是主要的不育治疗方法。总共有12次妊娠是通过家庭阴道授精实现的，8次是通过子宫内授精，2次是使用射出精子进行IVF，2次是使用从输精管抽吸的精子进行IVF。3对夫妇通过供体授精生育了孩子（结果中未计入）；12对夫妇仍在该治疗方案中。在最初的35对夫妇中，目前已有18对夫妇通过24次妊娠生育了22名儿童（51%），还有4次流产。因此，总体而言，脊髓损伤男性的不育治疗取得了良好效果。
