Sahjpaul R L, Ramsay D A, de Veber L L, Del Maestro R F
Dept. of Clinical Neurological Sciences, Victoria Hospital, London, Ontario, Canada.
J Neurooncol. 1993 Jun;16(3):221-6. doi: 10.1007/BF01057037.
We describe a 5 year old boy with a 5.5 cm right frontal lobe brain metastasis from primary clear cell sarcoma of the kidney without evidence of tumor-associated edema or contrast enhancement on either computed tomography or magnetic resonance imaging. The metastasis regressed but did not disappear with chemotherapy and dexamethasone, and the residual tumor was removed surgically. On histological examination the majority of the tumor was composed of mature connective tissue with a rim of typical renal clear cell sarcoma cells at the brain-tumor interface. The avascular and desmoplastic nature of the metastasis may explain the unusual radiographic features. Brain metastases from this tumor have only infrequently been reported; therefore a brief review of this rare tumor is provided.
我们描述了一名5岁男孩，患有源自肾原发性透明细胞肉瘤的5.5厘米右额叶脑转移瘤，计算机断层扫描或磁共振成像均未显示肿瘤相关水肿或对比增强迹象。该转移瘤经化疗和地塞米松治疗后缩小但未消失，残余肿瘤通过手术切除。组织学检查显示，大部分肿瘤由成熟结缔组织构成，在脑肿瘤界面处有一圈典型的肾透明细胞肉瘤细胞。转移瘤的无血管和促结缔组织增生特性可能解释了其不寻常的影像学特征。这种肿瘤的脑转移瘤报道较少；因此，本文对这种罕见肿瘤进行简要综述。
