Ma L, Iani V, Moan J
Department of Biophysics, Institute for Cancer Research, Oslo, Norway.
J Photochem Photobiol B. 1993 Dec;21(2-3):149-54. doi: 10.1016/1011-1344(93)80177-b.
The interactions of pairs of the modalities Photofrin II-sensitized photochemotherapy (PCT), ionizing radiation and an electric current were investigated by the colony formation assay in WiDr cells, a human colon adenocarcinoma cell line. When the cells were treated simultaneously with PCT and an electric current, a slightly synergistic effect was observed at low exposures (surviving fraction approximately 0.1) while a seemingly antagonist effect was found at higher exposures. The same was found to be true for the combinations of PCT plus ionizing radiation and ionizing radiation plus electric current.
