Cooper R S
Department of Preventive Medicine and Epidemiology, Loyola University Medical School, Maywood, IL 60153.
Public Health Rep. 1994 Jan-Feb;109(1):46-52.
Increased attention has been focused on the use of racial and ethnic categories in public health research and surveillance in recent years. This attention, however, has done more to increase the collective awareness of the difficulties inherent in these classification schemes than to resolve either the theoretical or practical problems. It has been recognized for many years that health outcomes for a particular ethnic population must be seen as an interaction between genetically determined factors and socially mediated exposures. The operational meaning of these concepts remains poorly defined, however. Although the general biologic construct of race and ethnicity appears straightforward, appearance is deceiving and the technical requirements that allow formulation of a rigorous and objective working definition have never been fully developed. The social factors that influence ethnic health differentials are perhaps better understood in practical terms; measurement of many of the relevant variables remains difficult, however. In this article an attempt is made to outline the implications of the new developments in molecular biology for the concept of race, and to provide an illustrative example of the continued evolution of the social determinants of ethnicity.
近年来,公共卫生研究与监测中对种族和族裔类别的使用受到了越来越多的关注。然而,这种关注更多地是提高了人们对这些分类体系中固有困难的集体认识,而不是解决理论或实际问题。多年来人们已经认识到,特定族裔人群的健康结果必须被视为基因决定因素与社会介导暴露之间的相互作用。然而,这些概念的实际含义仍然界定不清。尽管种族和族裔的一般生物学概念看起来很简单,但表象具有欺骗性,能够形成严格且客观的工作定义的技术要求从未得到充分发展。影响族裔健康差异的社会因素或许从实际角度能得到更好的理解;然而,许多相关变量的测量仍然困难。在本文中,我们试图概述分子生物学新进展对种族概念的影响,并提供一个族裔社会决定因素持续演变的示例。