Krausz M, Müller-Thomsen T
Universitätskrankenhaus Eppendorf (UKE), Psychiatrische Klinik, Hamburg, Germany.
Schizophr Bull. 1993;19(4):831-41. doi: 10.1093/schbul/19.4.831.
This study examined the course of illness and factors affecting it in schizophrenias with onset between the ages of 14 and 18. Noteworthy in comparison to findings from other followup studies is the higher proportion of chronic courses of illness, about 50 percent. In addition, the type of course of illness corresponds in general with the treatment status. A possible explanation for this observation is the early age of onset, at which point the patient has not yet developed a sufficient degree of social and emotional independence and maturity before developing a schizophrenic psychosis. The age of onset is also shown to be an important predictor for the overall course of illness, as in other studies.
本研究调查了发病年龄在14岁至18岁之间的精神分裂症患者的病程及影响病程的因素。与其他随访研究的结果相比，值得注意的是，慢性病程的比例较高，约为50%。此外，病程类型总体上与治疗状况相符。对这一观察结果的一种可能解释是发病年龄较早，此时患者在患上精神分裂症性精神病之前尚未发展出足够程度的社会和情感独立性及成熟度。与其他研究一样，发病年龄也是疾病总体病程的一个重要预测指标。
