Nityanand S, Pande I, Bajpai V K, Singh L, Chandra M, Singh B N
Department of Medicine, King George's Medical College, Lucknow, India.
Thromb Res. 1993 Dec 1;72(5):447-54. doi: 10.1016/0049-3848(93)90245-j.
The ultrastructure and adenosine diphosphate induced aggregatory response of platelets of 39 patients with essential hypertension have been studied. Both, transmission and scanning electron microscopy showed the co-existence of various morphological forms of platelets suggestive of activation. The hypertensive platelets also exhibited increased sensitivity to ADP induced aggregation confirming the activated state of platelets; the degree of activation correlated well with the levels of diastolic blood pressure.
对39例原发性高血压患者血小板的超微结构及二磷酸腺苷诱导的聚集反应进行了研究。透射电子显微镜和扫描电子显微镜均显示存在多种提示血小板活化的形态学形式。高血压患者的血小板对ADP诱导的聚集也表现出更高的敏感性，证实了血小板的活化状态；活化程度与舒张压水平密切相关。
