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预测首次中风患者1年后的残疾情况。对英格兰东南部一个基于人群的队列进行12个月随访。

Predicting the disability of first-time stroke sufferers at 1 year. 12-month follow-up of a population-based cohort in southeast England.

作者信息

Taub N A, Wolfe C D, Richardson E, Burney P G

机构信息

Division of Community Health, United Medical School, Guy's Hospital, London, England.

出版信息

Stroke. 1994 Feb;25(2):352-7. doi: 10.1161/01.str.25.2.352.

Abstract

BACKGROUND AND PURPOSE

The purpose of this study was to predict the functional outcome at 1 year of first-time stroke patients aged younger than 75 years in relation to the severity of stroke and demographic characteristics.

METHODS

Population registers in three districts of southeast England were established in August 1989, with notification by stroke registry field-workers, general practitioners, and rehabilitation practitioners. Assessments were made using the Barthel index for activities of daily living at the time of maximum impairment and at 3 and 12 months after the stroke.

RESULTS

Of 639 registered stroke patients, 392 without previous disability survived and were assessed for disability at 3 months, of whom 34 (9%) were severely disabled and 60 (15%) moderately disabled. Initial incontinence was the best single predictor of disability with a sensitivity of 60% and a specificity of 78%. Two hundred twenty-five patients (35%) were eligible for 12-month follow-up; 11% had moderate or severe disability, for which initial incontinence was the best predictor.

CONCLUSIONS

There is no evidence from this study of an association between demographic characteristics and the disability status of stroke survivors in the medium term. Multivariable predictors of disability had little advantage over incontinence within 24 hours of the stroke. The estimates of the prevalence of disability from this large population-based study are relevant when assessing the medium-term needs of stroke patients.

摘要

背景与目的

本研究旨在预测年龄小于75岁的首次卒中患者1年时的功能结局,探讨其与卒中严重程度及人口统计学特征的关系。

方法

1989年8月在英格兰东南部三个地区建立了人口登记册,由卒中登记现场工作人员、全科医生和康复从业者进行通知。在最大功能障碍时以及卒中后3个月和12个月时,使用巴氏指数对日常生活活动能力进行评估。

结果

在639例登记的卒中患者中,392例既往无残疾的患者存活并在3个月时接受了残疾评估,其中34例(9%)为重度残疾,60例(15%)为中度残疾。初始失禁是残疾的最佳单一预测因素,敏感性为60%,特异性为78%。225例患者(35%)符合12个月随访条件;11%有中度或重度残疾,初始失禁是其最佳预测因素。

结论

本研究没有证据表明人口统计学特征与卒中幸存者中期残疾状况之间存在关联。在卒中24小时内,残疾的多变量预测因素相比失禁并无明显优势。在评估卒中患者的中期需求时,这项基于大量人群的研究中残疾患病率的估计具有参考价值。

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