阿霉素对中国仓鼠卵巢细胞的细胞周期进程和DNA复制的影响。
The effect of adriamycin on cell cycle progression and DNA replication in chinese hamster ovary cells.
作者信息
Clarkson J M, Humphrey R M
出版信息
Cancer Res. 1977 Jan;37(1):200-5.
PMID:830405
Abstract
Administration of[3H]aflatoxin B2 (2,3-dihydroaflatoxin B1)(AFB2) to male rats resulted in levels of hepatic DNA- and ribosomal (r)RNA-aflatoxin adducts that were about 1% of those for rats given [3H]aflatoxin B1(AFB1). The levels of hepatic protein-aflatoxin adducts were 35 to70% as great for AFB2-treated as compared to AFB1-treated rats...
摘要
给雄性大鼠施用[3H]黄曲霉毒素B2（2,3-二氢黄曲霉毒素B1）（AFB2）后，肝脏DNA和核糖体（r）RNA-黄曲霉毒素加合物的水平约为给予[3H]黄曲霉毒素B1（AFB1）的大鼠的1%。与AFB1处理的大鼠相比，AFB2处理的大鼠肝脏蛋白质-黄曲霉毒素加合物的水平为其35%至70%……
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