Simpson J K, Mills W, Spittle M F
Meyerstein Institute of Clinical Oncology, Middlesex Hospital, London, UK.
Clin Oncol (R Coll Radiol). 1993;5(6):375-7. doi: 10.1016/s0936-6555(05)80090-1.
High grade non-Hodgkin's lymphoma accounts for only 5%-10% of all non-Hodgkin's lymphoma. Infection with the human immunodeficiency virus increases the risk of developing high grade, usually B-cell, lymphoma, which has been noted to occur more commonly in homosexual men. These lymphomas often have unusual clinical presentations. We report five cases of high grade non-Hodgkin's lymphoma in HIV negative homosexual men who presented to our hospital in a 13-month period. As a major centre for the treatment of the acquired immune deficiency syndrome, there may be a self-selected homosexual population attending for medical care, and thus a bias in the relative incidence of lymphoma seen in this group.
高级别非霍奇金淋巴瘤仅占所有非霍奇金淋巴瘤的5%-10%。感染人类免疫缺陷病毒会增加患高级别淋巴瘤（通常为B细胞淋巴瘤）的风险，这种淋巴瘤在同性恋男性中更为常见。这些淋巴瘤往往有不寻常的临床表现。我们报告了5例在13个月期间到我院就诊的HIV阴性同性恋男性高级别非霍奇金淋巴瘤病例。作为获得性免疫缺陷综合征的主要治疗中心，前来就医的同性恋人群可能存在自我选择的情况，因此该组中淋巴瘤的相对发病率可能存在偏差。
