Novotný J, Placheta Z, Dohnalová I
Kninika funkcní diagnostiky a tĕlovýchovného lékarství LF MU, Brno.
Cas Lek Cesk. 1993 Dec 20;132(24):756-9.
The authors investigated and compared the response of 26 men with insulin dependent diabetes mellitus to a physical load in the laboratory (bicycle spiroergometry with a work load graded up to a maximum) and recommended 20 min. walking or running under field conditions (constant speed beneath the "anaerobic threshold"). The mean maximal oxygen uptake per minute in the laboratory (2.81 +/- 0.47 l) was insignificantly lower than reference values and combined with the maximal minute heart rate (mean 175 +/- 17) very variable. During the load under field conditions the oxygen uptake practically did not change (1.64 +/- 0.59 l/min.) but the heart rate increased due to the declining stroke volume. The blood sugar level in the laboratory and during field exercise declined significantly. In the laboratory the base deficit and lactacidaemia increased markedly; under field conditions their concentration increased slightly and did not pass the anaerobic threshold level. The pyruvate, acetoacetate and beta-OH-butyrate concentrations did not change much and were consistent with the response of well controlled diabetic patients.
作者们对26名胰岛素依赖型糖尿病男性患者在实验室中对体力负荷的反应进行了研究和比较（进行自行车运动心肺功能测试，工作量逐渐增加至最大值），并建议在野外条件下进行20分钟的步行或跑步（速度恒定在“无氧阈值”以下）。实验室中每分钟的平均最大摄氧量（2.81±0.47升）略低于参考值，且与最大分钟心率（平均175±17）结合起来变化很大。在野外条件下的负荷过程中，摄氧量实际上没有变化（1.64±0.59升/分钟），但由于每搏输出量下降，心率增加。实验室和野外运动期间的血糖水平显著下降。在实验室中，碱缺失和乳酸血症明显增加；在野外条件下，它们的浓度略有增加，且未超过无氧阈值水平。丙酮酸、乙酰乙酸和β-羟基丁酸的浓度变化不大，与病情得到良好控制的糖尿病患者的反应一致。
