心包内注射丝裂霉素C治疗胃癌继发恶性心包积液：病例报告及文献复习

Intrapericardial mitomycin C for the management of malignant pericardial effusion secondary to gastric cancer: case report and review.

作者信息

Kohnoe S, Maehara Y, Takahashi I, Saito A, Okada Y, Sugimachi K

机构信息

Department of Surgery, and Medicine, Social Health Insurance Nakabaru Hospital, Fukuoka, Japan.

出版信息

Chemotherapy. 1994 Jan-Feb;40(1):57-60. doi: 10.1159/000239171.

DOI:10.1159/000239171

PMID:8306816

Abstract

In a 57-year-old man with recurrent gastric cancer, cardiac tamponade due to malignant pericardial effusion developed. Echocardiographically guided pericardiocentesis followed by an intrapericardial instillation of mitomycin C provided a complete control of the pericardial effusion, and no adverse effects were observed with this procedure. An intrapericardial instillation with effective anticancer agents is therefore considered to be useful for the management of malignant pericardial effusion.

摘要

一名57岁复发性胃癌男性患者出现了因恶性心包积液导致的心脏压塞。在超声心动图引导下进行心包穿刺术，随后在心包腔内注入丝裂霉素C，使心包积液得到了完全控制，且该操作未观察到不良反应。因此，心包腔内注入有效的抗癌药物被认为对恶性心包积液的治疗有用。