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转移因子疗法治疗特应性皮炎失败。

Failure of transfer factor therapy in atopic dermatitis.

作者信息

Hovmark A, Ekre H P

出版信息

Acta Derm Venereol. 1978;58(6):497-500.

PMID:83072
Abstract

A controlled clinical study was conducted on 6 patients with atopic dermatitis to assess the efficacy of transfer factor. After the code was broken the 3 patients treated with placebo preparation were treated with transfer factor for a further period of 10 weeks. No definite therapeutic effects could be demonstrated. The immunological in vivo and in vitro tests failed to reveal any effects except for a change to positive in the tuberculin skin test in those patients who had previously been skin test negative. The treatment had to be discontinued in one patient due to a suspected allergic reaction against transfer factor.

摘要

对6例特应性皮炎患者进行了一项对照临床研究,以评估转移因子的疗效。在揭盲后,3例接受安慰剂制剂治疗的患者又接受了10周的转移因子治疗。未显示出明确的治疗效果。体内和体外免疫学检测均未发现任何效果,只有那些先前结核菌素皮肤试验阴性的患者其结核菌素皮肤试验转为阳性。有1例患者因怀疑对转移因子过敏反应而不得不停止治疗。

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引用本文的文献

1
Treatment of atopic dermatitis: old and new modalities.特应性皮炎的治疗:新旧方法
Clin Rev Allergy. 1986 Feb;4(1):87-99. doi: 10.1007/BF02991189.