Jakubczak L F
J Gerontol. 1977 Jan;32(1):49-57. doi: 10.1093/geronj/32.1.49.
Is there an age-related decrement in the regulation of calorie intake? The results of Experiment I indicated that there was an age-related decrement in calorie intake and body weight of rats in response to dilution of their diet with non-nutritive cellulose. Was this decrement due to an age-related increase in reactivity to the sensory and hedonic aspects of the adulterated diet? The results of Experiment II indicated that older rats maintained their calorie intake and body weight as well as younger rats in response to dilution of their diet with water but decreased their calorie intake and body weight to a greater degree than younger rats when the water-diet mixture was adulterated by quinine. The results of these experiments suggest that the regulation of calorie intake remains intact over a large segment of the life of the rat, but can be overridden by age-related increases in reactivity to the sensory and hedonic aspects of the diet.
卡路里摄入量的调节是否存在与年龄相关的下降？实验一的结果表明，用无营养的纤维素稀释大鼠饮食后，大鼠的卡路里摄入量和体重存在与年龄相关的下降。这种下降是由于对掺假饮食的感官和享乐方面的反应性随年龄增长而增加吗？实验二的结果表明，用清水稀释饮食时，老年大鼠能像年轻大鼠一样维持其卡路里摄入量和体重，但当水 - 饮食混合物被奎宁掺假时，老年大鼠的卡路里摄入量和体重下降幅度比年轻大鼠更大。这些实验结果表明，在大鼠生命的大部分阶段，卡路里摄入量的调节保持完好，但饮食的感官和享乐方面的反应性随年龄增长而增加可能会使其失效。
