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沙特阿拉伯努尔专科医院患者利什曼原虫分离株的同工酶特征分析

Isoenzyme characterization of Leishmania isolates from patients in El Nour Specialized Hospital, Saudi Arabia.

作者信息

Morsy T A, Sarwat M A, al Shaiby A Z, Fawzy A F, Arafa M A

机构信息

Department of Parasitology, Faculty of Medicine, Ain Shams University, Abbassia, Cairo, Egypt.

出版信息

J Egypt Soc Parasitol. 1993 Dec;23(3):871-6.

PMID:8308362
Abstract

No doubt, the three forms of leishmaniasis (VL, ZCL & ACL) are well documented in Saudi Arabia. The basis of epidemiological studies must be adequate identification of the Leishmania patients. Seven leishmanial strains have been isolated from patients attending El Nour Specialized Hospital, Makka Al Mokarrama. The majority of the patients of this hospital are temporary visitors to Makka Al Mokarrama for "Haj and Omra". Isoenzyme characterization by cellulose acetate electrophores's used nine enzymes was done. The seven isolates were: two L. donovani zymodeme LON 41 (Indian patient) and LON 46 (Sudanese patient); three L. tropica zymodeme LON 71 (2 Yemeri patients) and LON 22 (Egyptian patient) and two L. major zymodeme LON 4 (2 Saudi patients).

摘要

毫无疑问,利什曼病的三种形式(内脏利什曼病、皮肤粘膜利什曼病和皮肤利什曼病)在沙特阿拉伯都有充分记载。流行病学研究的基础必须是对利什曼病患者进行充分识别。从麦加穆卡拉马的努尔专科医院就诊的患者中分离出了7株利什曼原虫菌株。这家医院的大多数患者都是来麦加穆卡拉马进行“朝觐和副朝”的临时访客。通过醋酸纤维素电泳对9种酶进行了同工酶鉴定。这7个分离株分别是:2株杜氏利什曼原虫酶型LON 41(印度患者)和LON 46(苏丹患者);3株热带利什曼原虫酶型LON 71(2名也门患者)和LON 22(埃及患者);以及2株硕大利什曼原虫酶型LON 4(2名沙特患者)。

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