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手部、髋部影像学骨关节炎及腰椎间盘退变新指标的可靠性。

Reliability of new indices of radiographic osteoarthritis of the hand and hip and lumbar disc degeneration.

作者信息

Lane N E, Nevitt M C, Genant H K, Hochberg M C

机构信息

Department of Medicine, University of California, San Francisco 94143-0868.

出版信息

J Rheumatol. 1993 Nov;20(11):1911-8.

PMID:8308778
Abstract

OBJECTIVE

To develop a method for assessing the presence and severity of radiographic features of osteoarthritis (OA) of the hip and hand, and thoracic and lumbar disc degeneration.

METHODS

An atlas illustrating scoring of individual radiographic features and summary grades for individual joints was developed. Three readers evaluated 31 pelvic films, 27 hand films, and 25 lateral lumbar and thoracic spine films selected from a community based sample of healthy elderly women. Interrater agreement between the 3 readers, and test-retest agreement for one of the readers, were estimated by the intraclass correlation coefficient (ICC) and kappa statistic.

RESULTS

Interrater agreement (ICC, unless otherwise noted) for individual radiographic features of the hip ranged from 0.66 for osteophytes to 0.80 for narrowing. For the 9 interphalangeal (IP) joints of the hand, agreement ranged from 0.42 (kappa) for sclerosis to 0.93 for narrowing, and for the lumbar spine from 0.55 (kappa) for sclerosis to 0.95 for narrowing. Interrater agreement for summary grades of radiographic findings was as follows: hip, 0.81; 5 distal interphalangeal joints (DIP), 0.89; 4 proximal interphalangeal joints (PIP), 0.82; and lumbar spine, 0.93. Intrarater agreement for summary grades was as follows: hips, 0.79; 5 DIP, 0.86; 4 PIP, 0.81; and lumbar spine, 0.90.

CONCLUSION

We have developed reliable indices of the presence and severity of radiographic features of hip and hand OA and spinal disc degeneration for use in epidemiologic studies. The assessment includes grading of individual radiographic features, which allows for the independent variation in these features often found in OA and a summary grade of disease that is derived from the presence and severity of individual features.

摘要

目的

开发一种用于评估髋部、手部骨关节炎(OA)以及胸腰椎间盘退变的影像学特征的存在情况及严重程度的方法。

方法

编制了一本图谱,展示了各个影像学特征的评分以及各个关节的综合分级。三名阅片者对从健康老年女性社区样本中选取的31张骨盆X线片、27张手部X线片以及25张腰椎和胸椎侧位X线片进行评估。通过组内相关系数(ICC)和kappa统计量来估计三名阅片者之间的评分者间一致性,以及其中一名阅片者的重测一致性。

结果

髋部各个影像学特征的评分者间一致性(ICC,除非另有说明),骨赘为0.66,关节间隙变窄为0.80。手部9个指间关节(IP),硬化的一致性为0.42(kappa),关节间隙变窄为0.93;腰椎的硬化一致性为0.55(kappa),关节间隙变窄为0.95。影像学检查结果综合分级的评分者间一致性如下:髋部为0.81;5个远端指间关节(DIP)为0.89;4个近端指间关节(PIP)为0.82;腰椎为0.93。综合分级的阅片者内一致性如下:髋部为0.79;5个DIP为0.86;4个PIP为0.81;腰椎为0.90。

结论

我们已经开发出了可靠的指标,用于评估髋部和手部OA以及脊柱椎间盘退变的影像学特征的存在情况及严重程度,可用于流行病学研究。该评估包括对各个影像学特征进行分级,这能够考虑到OA中这些特征常见的独立变化情况,以及基于各个特征的存在情况和严重程度得出的疾病综合分级。

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