Lane N E, Kremer L B
University of California, School of Medicine, San Francisco, USA.
Rheum Dis Clin North Am. 1995 May;21(2):379-94.
There are now validated radiographic indices that can be used by clinical investigators to determine the prevalence and severity of OA of the hand, hip, knee, apophyseal joints of the cervical and lumbar spine, and cervical disc degeneration. Clinical investigators should consult standardized atlases for radiographic index descriptions. The use of an atlas and training sessions improve the agreement between and within readers. The standard global grades developed by Kellgren and Lawrence have been used in epidemiologic studies to determine the prevalence of OA in specific joints. The evaluation of radiographic OA by individual radiographic features allows for the characterization of the variation in radiographic features often found in OA and in degenerative disc disease. Methods have been developed to maintain interrater and intrarater agreement in scoring radiographs. Radiographic indices of OA can now be reliably applied to clinical epidemiologic-based studies of OA.
现在有经过验证的影像学指标,临床研究人员可以用其来确定手部、髋部、膝部、颈椎和腰椎的关节突关节以及颈椎间盘退变的骨关节炎患病率和严重程度。临床研究人员应查阅标准化图谱以获取影像学指标描述。使用图谱和培训课程可提高读者之间以及读者内部的一致性。Kellgren和Lawrence制定的标准整体分级已用于流行病学研究,以确定特定关节的骨关节炎患病率。通过单个影像学特征对影像学骨关节炎进行评估,有助于描述骨关节炎和椎间盘退变中常见的影像学特征变化。现已开发出一些方法来保持在对X线片评分时的评分者间和评分者内一致性。骨关节炎的影像学指标现在可以可靠地应用于基于临床流行病学的骨关节炎研究。