Gleadle J, Dixon C, Brown M M, Schon F
Atkinson Morley's Hospital, Wimbledon, UK.
J R Soc Med. 1994 Jan;87(1):7-8. doi: 10.1177/014107689408700105.
The early use of intravenous acyclovir in herpes simplex encephalitis (HSE) is essential. However, rapid diagnostic tests are not freely available. Hence, all patients with suspected encephalitis may need to be commenced on acyclovir. In our study, of 34 patients with suspected encephalitis, only two eventually had HSE confirmed, 19 had encephalitis not due to herpes simplex and in 13 a non-encephalitis illness was finally diagnosed. Guidelines for the use of acyclovir in suspected encephalitis are given aimed at minimizing the drug cost whilst still protecting all cases of presumed HSE.
早期静脉使用阿昔洛韦治疗单纯疱疹病毒性脑炎（HSE）至关重要。然而，快速诊断检测并非随时可用。因此，所有疑似脑炎的患者可能都需要开始使用阿昔洛韦。在我们的研究中，34例疑似脑炎患者中，最终仅2例确诊为HSE，19例为非单纯疱疹病毒性脑炎，13例最终被诊断为非脑炎疾病。本文给出了疑似脑炎患者使用阿昔洛韦的指南，旨在在保护所有疑似HSE病例的同时尽量降低药物成本。
