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前列腺胚胎性横纹肌肉瘤

Embryonal rhabdomyosarcoma of the prostate.

作者信息

King D G, Finney R P

出版信息

J Urol. 1977 Jan;117(1):88-90. doi: 10.1016/s0022-5347(17)58351-2.

DOI:10.1016/s0022-5347(17)58351-2
PMID:830977
Abstract

Embryonal rhabdomyosarcoma of the prostate is typically a rare mesenchymal tumor of young boys, presenting with obstructive urinary symptoms or an abdominal mass. The origin is probably in undifferentiated mesenchymal cells that persist into adult life. Histologically, the tumor cells resemble normal muscle development in a 7 to 10-week fetus. Treatment is combined radical surgery and chemotherapy, and usually radiotherapy as well. The prognosis is extremely poor in all patients. Our case is added to the few in the literature in which this disease occurred in a man more than 50 years old.

摘要

前列腺胚胎性横纹肌肉瘤通常是一种发生于男童的罕见间叶组织肿瘤,表现为尿路梗阻症状或腹部肿块。其起源可能是持续至成年期的未分化间叶细胞。组织学上,肿瘤细胞类似于7至10周胎儿的正常肌肉发育情况。治疗方法为根治性手术联合化疗,通常还需放疗。所有患者的预后都极差。我们的病例补充了文献中少数该疾病发生于50岁以上男性的案例。

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引用本文的文献

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Demographics, stage distribution, and relative roles of surgery and radiotherapy on survival of persons with primary prostate sarcomas.原发性前列腺肉瘤患者的人口统计学、分期分布以及手术和放疗的相对作用。
Cancer Med. 2018 Dec;7(12):6030-6039. doi: 10.1002/cam4.1872. Epub 2018 Nov 19.
2
Primary embryonal rhabdomyosarcoma of prostate in adults: diagnosis and management.成人前列腺原发性胚胎性横纹肌肉瘤:诊断与治疗
Int Urol Nephrol. 2002;34(4):531-4. doi: 10.1023/a:1025638711476.