Vargas M A, Davidson J
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina.
Psychiatr Clin North Am. 1993 Dec;16(4):737-48.
In the past few years, there has been a growing interest in the neurobiology of PTSD. A number of models have been proposed including possible structural changes. We have now seen the appearance in the literature of controlled and double-blind trials. Of interest are positive outcome studies associated with the use of drugs with serotonergic actions for a period of 8 weeks. Symptom relief provided by pharmacotherapy enables the patient to participate more thoroughly in individual, behavioral, or group therapy.
在过去几年里,人们对创伤后应激障碍(PTSD)的神经生物学越来越感兴趣。已经提出了一些模型,包括可能的结构变化。我们现在已经看到文献中出现了对照试验和双盲试验。有趣的是,与使用具有血清素能作用的药物长达8周相关的积极结果研究。药物治疗提供的症状缓解使患者能够更全面地参与个体、行为或团体治疗。