Korczyk P, Hoszowski K, Tałajko A, Lorenc R S
II Oddziału Wewnetrznego Szpitala Kolejowego, Warszawie.
Pol Tyg Lek. 1993 Nov;48 Suppl 3:28-30.
The study aimed at evaluating precision of ultrasound measurements of mineral bone density of the calcaneus, and evaluating correlation between the obtained results with those measured with single photon absorptiometry (SPA) and DEXA in different skeletal sites. In 24 healthy individuals and 44 patients with osteoporosis SOS, BUA, calcaneus stiffness index, spine bone mineral density (L2-L4), femoral neck and calcaneal bone mineral densities were measured with DEXA technique whereas BMD in distal radial bone was measured with SPA. Very good precision of ultrasound measurements--better for SOS (CV = 0.12%), worse for BUA (CV = 1.64%) due to repositioning--was achieved. Statistically significant correlation between ultrasound and DEXA measurements of BMD in calcaneus bone (r = 0.90), and significant but worse correlations with BMD measurements for the spine (r = 0.43), femoral bone neck (r = 0.53), and 1/3 radius, (r = 0.51) were achieved. Ultrasound measurements of bone mineral density have low error of repeatability and good accuracy, enabling to discriminate healthy individuals from osteoporosis patients.
该研究旨在评估超声测量跟骨骨密度的精度,并评估所获结果与不同骨骼部位单光子吸收测定法(SPA)和双能X线吸收法(DEXA)测量结果之间的相关性。对24名健康个体和44名骨质疏松症患者,采用DEXA技术测量跟骨的声速(SOS)、宽带超声衰减(BUA)、跟骨硬度指数、脊柱骨密度(L2-L4)、股骨颈和跟骨骨密度,而采用SPA测量桡骨远端骨密度。超声测量具有非常好的精度——SOS精度更好(变异系数CV = 0.12%),由于重新定位BUA精度稍差(CV = 1.64%)。跟骨骨密度的超声测量与DEXA测量之间存在统计学显著相关性(r = 0.90),与脊柱(r = 0.43)、股骨颈(r = 0.53)和桡骨1/3处(r = 0.51)的骨密度测量也存在显著但稍弱的相关性。骨密度的超声测量具有低重复性误差和良好的准确性,能够区分健康个体和骨质疏松症患者。