Soubrane G, Coscas G
Clinique ophtalmologique universitaire, Université Paris XII, Créteil.
Rev Prat. 1993 Sep 15;43(14):1773-8.
High or degenerative myopia is associated to abnormalities of the posterior pole of the eye. Their expansion with time progresses to the occurrence of complications, especially neovascular ingrowth in the central macular area. The natural evolution of these new vessels results in loss of central vision at long term. Photocoagulation of the new vessels, sparing initially the center, has delayed the loss of central vision at 2 years in our randomized clinical trial. Only treated eyes retained useful acuity at 5 years. New therapeutic modalities will be possible when the mechanisms of occurrence of degenerative myopia are elucidated.
高度近视或退行性近视与眼球后极部异常有关。随着时间推移，这些异常会发展并引发并发症，尤其是黄斑中心区域的新生血管长入。这些新生血管的自然发展最终会导致长期中心视力丧失。在我们的随机临床试验中，对新生血管进行光凝治疗（最初避开中心区域）在两年内延缓了中心视力丧失。只有接受治疗的眼睛在5年后仍保留有用视力。当退行性近视的发病机制得以阐明时，将会出现新的治疗方法。
