Amodeo C, Martins S M, Silva Júnior O, Barros L M, Batlouni M, Sousa J E
Instituto Dante Pazzanese de Cardiologia, Hospital do Coração, Ass. San. Sirio, SP.
Arq Bras Cardiol. 1993 May;60(5):289-91.
To evaluate the left ventricular hypertrophy correlation with blood pressure variability during day and night time as well as throughout the 24h period.
Fifteen patients with mild to moderate essential hypertension underwent to bi-dimensional echocardiographic study and to 24h ambulatory blood pressure monitorization. Left ventricular mass was calculated according to previous validated formulas. The standard deviation of the mean blood pressures during day-time, night-time and 24h period was taken as blood pressure variability indices. The mean age of the group was 42 years old; 9 patients were male and all were white.
This study showed that only the systolic and diastolic blood pressure variability during the 24h period correlated significantly with left ventricular mass, (r = 0.53 and p < 0.05; r = 0.58 and p < 0.05 respectively). There was no significant correlation of the day-time and night-time pressures variability with left ventricular mass.
The systolic and diastolic blood pressure variability during the 24h period may be one of the many determinants of left ventricular hypertrophy in patients with mild to moderate hypertension.
评估左心室肥厚与日间、夜间以及整个24小时期间血压变异性的相关性。
15例轻度至中度原发性高血压患者接受了二维超声心动图检查和24小时动态血压监测。根据先前验证的公式计算左心室质量。将日间、夜间和24小时期间平均血压的标准差作为血压变异性指标。该组患者的平均年龄为42岁；9例为男性，均为白人。
本研究表明，仅24小时期间的收缩压和舒张压变异性与左心室质量显著相关（分别为r = 0.53，p < 0.05；r = 0.58，p < 0.05）。日间和夜间血压变异性与左心室质量无显著相关性。
24小时期间的收缩压和舒张压变异性可能是轻度至中度高血压患者左心室肥厚的众多决定因素之一。
