De Potter P, Shields C L, Shields J A, Singh A D
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pa.
Arch Ophthalmol. 1994 Feb;112(2):208-12. doi: 10.1001/archopht.1994.01090140084028.
There is always a hesitancy to use an ocular implant after enucleation in children, especially in cases of eyes enucleated for retinoblastoma.
In this prospective study, we report our experience of 60 consecutive cases in which we used the hydroxyapatite ocular implant after enucleation in children younger than age 10 years.
The mean age at the time of enucleation and hydroxyapatite placement was 27 months (range, 1 to 108 months). The histopathologic diagnoses after enucleation included retinoblastoma in 51 patients, endophthalmitis in two patients, persistent hyperplastic primary vitreous in two patients, neovascular glaucoma resulting from Coats' disease in one patient, uveal melanoma in two patients, undifferentiated intraocular neoplasm in one patient, and blind painful traumatized eye in one patient. After a mean follow-up of 19 months (range, 6 to 36 months), two cases of conjunctival erosion and five cases of conjunctival thinning were recorded. These problems were associated with a flat posterior prosthesis vault in all seven cases. There were no cases of orbital cellulitis, implant extrusion, or implant migration. All children showed good small-degree prosthesis motility despite the lack of peg placement. Only one older child underwent drilling and peg placement and she had excellent small- and large-degree prosthesis motility. We generally postpone the drilling and peg placement stage and tedious prosthesis revision in children until they are able to fully cooperate with the ocularist.
The hydroxyapatite ocular implant is well tolerated and provides good prosthesis motility in children with few complications. It is critical for the ocularist to fit the prosthesis comfortably with a high posterior vault.
儿童眼球摘除术后使用眼内植入物一直存在犹豫,尤其是因视网膜母细胞瘤而摘除眼球的病例。
在这项前瞻性研究中,我们报告了连续60例10岁以下儿童眼球摘除术后使用羟基磷灰石眼内植入物的经验。
摘除眼球及植入羟基磷灰石时的平均年龄为27个月(范围1至108个月)。摘除眼球后的组织病理学诊断包括51例视网膜母细胞瘤、2例眼内炎、2例持续性增生性原发性玻璃体、1例因科茨病导致的新生血管性青光眼、2例葡萄膜黑色素瘤、1例未分化眼内肿瘤以及1例盲目疼痛的外伤眼。平均随访19个月(范围6至36个月)后,记录到2例结膜糜烂和5例结膜变薄。在所有7例病例中,这些问题都与义眼座后穹窿扁平有关。没有眼眶蜂窝织炎、植入物挤出或植入物移位的病例。尽管未放置栓钉,但所有儿童的义眼座均有良好的小幅度活动度。只有一名年龄较大的儿童接受了钻孔和栓钉植入,她的义眼座在小幅度和大幅度活动时均表现出色。我们通常会推迟儿童的钻孔和栓钉植入阶段以及繁琐的义眼修复,直到他们能够与眼科整形师充分配合。
羟基磷灰石眼内植入物耐受性良好,在儿童中能提供良好的义眼座活动度,并发症较少。对于眼科整形师来说,将义眼座舒适地适配成高后穹窿至关重要。